CureVac and Novartis Sign Initial Agreement on Manufacturing of COVID-19 Vaccine
Candidate, CVnCoV
? Novartis plans to start manufacturing of the mRNA and bulk drug product of CureVac’s COVID-19
vaccine candidate, CVnCoV, in Q2 2021
? Anticipated production of up to 50 million doses by the end of 2021 and up to a further 200
million doses in 2022 at the Novartis’ manufacturing site in Kundl, Austria
? Further expansion of CureVac´s European manufacturing network expected to increase capacity
TÜBINGEN, Germany/ BOSTON, USA – March 04, 2021 – CureVac N.V. (Nasdaq: CVAC), a global
biopharmaceutical company developing a new class of transformative medicines based on messenger
ribonucleic acid (mRNA), and Novartis AG announced today that they have signed an initial agreement
for the manufacturing of CureVac’s COVID-19 vaccine candidate, CVnCoV. Preparations for the start of
production, technology transfers and test runs are already underway. Following final agreement,
Novartis plans to manufacture the mRNA and bulk drug product of the CVnCoV vaccine candidate for up
to 50 million doses by the end of 2021 and up to a further 200 million doses in 2022. Delivery from the
manufacturing site in Kundl, Austria, is expected to start in summer 2021.
Dr. Florian von der Mülbe, Chief Production Officer of CureVac, says: “I am very pleased that with
Novartis we have found another highly experienced partner to support the production of our vaccine
candidate. Together with Novartis we expect to increase significantly our manufacturing capacity and
place our production network on an even broader base.”
Steffen Lang, Global Head of Novartis Technical Operations and member of Executive Committee
Novartis, adds: “We feel it is our responsibility to do everything in our power to help and we are pleased
to announce our collaboration with CureVac. At the Kundl site, Novartis is a pioneer and has decades of
experience in pharmaceutical production of proteins and in more recent years of nucleic acids. We are
currently expanding our site with additional capacities for the production of mRNA in order to best serve
the increasing demand.”
CureVac started building an integrated European vaccine manufacturing network with several CDMO
partners in the fall of 2020. So far, CureVac is working with Bayer, Fareva, Wacker and Rentschler,
among others.